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Statement - Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 1008010 - Statement - Consolidated Statements of Cash Flows (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 2101101 - Disclosure - Summary of Significant Accounting Policies and Implementation of New Financial Accounting Standard link:presentationLink link:calculationLink link:definitionLink 2202201 - Disclosure - Summary of Significant Accounting Policies and Implementation of New Financial Accounting Standard (Policies) link:presentationLink link:calculationLink link:definitionLink 2403401 - Disclosure - Summary of Significant Accounting Policies and Implementation of New Financial Accounting Standard (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2104102 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 2305301 - Disclosure - Revenue (Tables) link:presentationLink link:calculationLink link:definitionLink 2406402 - 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Disclosure - Acquisitions and Divestiture (Purchase Price Allocation) (Details) link:presentationLink link:calculationLink link:definitionLink 2414408 - Disclosure - Acquisitions and Divestiture (Purchase Price Allocation) (Details) link:presentationLink link:calculationLink link:definitionLink 2415409 - Disclosure - Acquisitions and Divestiture (Asset Acquisitions) (Details) link:presentationLink link:calculationLink link:definitionLink 2116104 - Disclosure - Collaborations and Other Arrangements link:presentationLink link:calculationLink link:definitionLink 2317303 - Disclosure - Collaborations and Other Arrangements (Tables) link:presentationLink link:calculationLink link:definitionLink 2418410 - Disclosure - Collaborations and Other Arrangements (Milestones (Deferred) Capitalized) (Details) link:presentationLink link:calculationLink link:definitionLink 2419411 - Disclosure - Collaborations and Other Arrangements (Net Product Revenue) (Details) link:presentationLink link:calculationLink link:definitionLink 2420412 - Disclosure - Collaborations and Other Arrangements (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2121105 - Disclosure - Asset Impairment, Restructuring, and Other Special Charges link:presentationLink link:calculationLink link:definitionLink 2322304 - Disclosure - Asset Impairment, Restructuring, and Other Special Charges (Tables) link:presentationLink link:calculationLink link:definitionLink 2423413 - Disclosure - Asset Impairment, Restructuring, and Other Special Charges - Schedule of Other Operating Cost and Expense, by Component (Details) link:presentationLink link:calculationLink link:definitionLink 2424414 - Disclosure - Asset Impairment, Restructuring, and Other Special Charges (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2125106 - Disclosure - Inventories link:presentationLink link:calculationLink link:definitionLink 2326305 - Disclosure - Inventories (Tables) link:presentationLink link:calculationLink link:definitionLink 2427415 - Disclosure - Inventories (Details) link:presentationLink link:calculationLink link:definitionLink 2128107 - Disclosure - Financial Instruments link:presentationLink link:calculationLink link:definitionLink 2329306 - Disclosure - Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 2430416 - Disclosure - Financial Instruments (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2431417 - Disclosure - Financial Instruments (Schedule of Effect of Risk Management) (Details) link:presentationLink link:calculationLink link:definitionLink 2432418 - Disclosure - Financial Instruments (Schedule of Fair Value Measurement) (Details) link:presentationLink link:calculationLink link:definitionLink 2433419 - Disclosure - Financial Instruments (Schedule of Short-term and Long-term Classification) (Details) link:presentationLink link:calculationLink link:definitionLink 2434420 - Disclosure - Financial Instruments (Schedule of Risk Management Instruments) (Details) link:presentationLink link:calculationLink link:definitionLink 2435421 - Disclosure - Financial Instruments (Schedule of Contractual Maturities) (Details) link:presentationLink link:calculationLink link:definitionLink 2436422 - Disclosure - Financial Instruments (Schedule of AFS Unrealized Gain (Loss)) (Details) link:presentationLink link:calculationLink link:definitionLink 2437423 - Disclosure - Financial Instruments (Schedule of Investment Portfolio Activity) (Details) link:presentationLink link:calculationLink link:definitionLink 2138108 - Disclosure - Goodwill and Other Intangibles link:presentationLink link:calculationLink link:definitionLink 2339307 - Disclosure - Goodwill and Other Intangibles (Tables) link:presentationLink link:calculationLink link:definitionLink 2440424 - Disclosure - Goodwill and Other Intangibles (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2441425 - Disclosure - Goodwill and Other Intangibles (Schedule of Finite-lived and Indefinite-lived Intangible Assets other than Goodwill) (Details) link:presentationLink link:calculationLink link:definitionLink 2442426 - Disclosure - Goodwill and Other Intangibles (Schedule of Amortization Expense) (Details) link:presentationLink link:calculationLink link:definitionLink 2443427 - Disclosure - Goodwill and Other Intangibles (Schedule of Estimated Amortization Expense) (Details) link:presentationLink link:calculationLink link:definitionLink 2144109 - Disclosure - Property and Equipment link:presentationLink link:calculationLink link:definitionLink 2345308 - Disclosure - Property and Equipment (Tables) link:presentationLink link:calculationLink link:definitionLink 2446428 - Disclosure - Property and Equipment (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2447429 - Disclosure - Property and Equipment (Schedule of Property and Equipment) (Details) link:presentationLink link:calculationLink link:definitionLink 2448430 - Disclosure - Property and Equipment (Schedule of Depreciation Expense) (Details) link:presentationLink link:calculationLink link:definitionLink 2449431 - Disclosure - Property and Equipment (Schedule of Geographic Information) (Details) link:presentationLink link:calculationLink link:definitionLink 2150110 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 2351309 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 2452432 - Disclosure - Leases (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2453433 - Disclosure - Leases (Impact of Leases to Consolidated Condensed Financial Statements) (Details) link:presentationLink link:calculationLink link:definitionLink 2454434 - Disclosure - Leases (Maturities of Operating Lease Liabilities) (Details) link:presentationLink link:calculationLink link:definitionLink 2454434 - Disclosure - Leases (Maturities of Operating Lease Liabilities) (Details) link:presentationLink link:calculationLink link:definitionLink 2155111 - Disclosure - Borrowings link:presentationLink link:calculationLink link:definitionLink 2356310 - 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Disclosure - Income Taxes (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2472445 - Disclosure - Income Taxes (Schedule of Composition of Income Tax Expense) (Details) link:presentationLink link:calculationLink link:definitionLink 2473446 - Disclosure - Income Taxes (Schedule of Deferred Tax Asset and Liabilities) (Details) link:presentationLink link:calculationLink link:definitionLink 2474447 - Disclosure - Income Taxes (Schedule of Cash Payments of Income Taxes) (Details) link:presentationLink link:calculationLink link:definitionLink 2475448 - Disclosure - Income Taxes (Schedule of Future Cash Payments Relating to the Toll Tax) (Details) link:presentationLink link:calculationLink link:definitionLink 2476449 - Disclosure - Income Taxes (Schedule of Reconciliation of Income Taxes) (Details) link:presentationLink link:calculationLink link:definitionLink 2477450 - Disclosure - Income Taxes (Schedule of Unrecognized Tax Benefits) (Details) link:presentationLink link:calculationLink link:definitionLink 2478451 - Disclosure - Income Taxes (Schedule of Income Tax (Benefit) Expense Related to Interest and Penalties) (Details) link:presentationLink link:calculationLink link:definitionLink 2179115 - Disclosure - Retirement Benefits link:presentationLink link:calculationLink link:definitionLink 2380313 - Disclosure - Retirement Benefits (Tables) link:presentationLink link:calculationLink link:definitionLink 2481452 - Disclosure - Retirement Benefits (Schedule of Benefit Obligations and Plan Assets and Funded Status) (Details) link:presentationLink link:calculationLink link:definitionLink 2482453 - Disclosure - Retirement Benefits (Schedule of Components in Consolidated Balance Sheets) (Details) link:presentationLink link:calculationLink link:definitionLink 2483454 - Disclosure - Retirement Benefits (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2484455 - Disclosure - Retirement Benefits (Schedule of Weighted Average Assumptions) (Details) link:presentationLink link:calculationLink link:definitionLink 2485456 - 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